John Hancock Group of Funds > John Hancock Funds II
Health Sciences Fund
$302.85M
Avg Monthly Net Assets
$268.23M
Total Assets
$88K
Total Liabilities
$268.14M
Net Assets
Health Sciences Fund is a Mutual Fund in John Hancock Funds II
from John Hancock Group of Funds,
based in Massachusetts,
United States of America.
The fund has one share class
and monthly net assets of $302.85M.
On July 29th, 2024 it reported 183 holdings, the largest
being Eli Lilly and Company (11.1%), UnitedHealth Group Incorporated (6.5%) and Thermo Fisher Scientific Inc. (4.6%).
Data provided by Fincoded.
Share Classes
| Name | Class/Contract ID | Ticker | Monthly Returns (2 years) |
|---|---|---|---|
| Class NAV | C000104936 |
Holdings
From latest NPORT-P, filed July 29th, 2024 for period ending May 31st, 2024.
Historic holdings data available from Fincoded.
| Name | Profile | Category | Country | Value $USD | # Shares | % of Fund |
|---|---|---|---|---|---|---|
| 10X GENOMICS INC COMMON STOCK USD.00001 (10x Genomics Inc.) | Long | Equity-common | US | $763K | 34K | 0.28 |
| ACADIA PHARMACEUTICALS INC COMMON STOCK USD.0001 (Acadia Pharmaceuticals Inc.) | Long | Equity-common | US | $216K | 14K | 0.08 |
| ACUMEN PHARMACEUTICALS INC COMMON STOCK USD.0001 (Acumen Pharmaceuticals Inc.) | Long | Equity-common | US | $45K | 15K | 0.02 |
| AGILENT TECHNOLOGIES INC COMMON STOCK USD.01 (Agilent Technologies Inc.) | Long | Equity-common | US | $3M | 22K | 1.06 |
| AGILON HEALTH INC COMMON STOCK USD.01 (agilon health Inc.) | Long | Equity-common | US | $249K | 40K | 0.09 |
| AGIOS PHARMACEUTICALS INC COMMON STOCK USD.001 (Agios Pharmaceuticals Inc.) | Long | Equity-common | US | $600K | 17K | 0.22 |
| AKERO THERAPEUTICS INC COMMON STOCK USD.0001 (Akero Therapeutics Inc.) | Long | Equity-common | US | $338K | 18K | 0.13 |
| ALECTOR INC COMMON STOCK USD.0001 (Alector Inc.) | Long | Equity-common | US | $75K | 15K | 0.03 |
| ALKERMES PLC COMMON STOCK USD.01 | Long | Equity-common | IE | $690K | 30K | 0.26 |
| ALLOGENE THERAPEUTICS INC COMMON STOCK USD.001 (Allogene Therapeutics Inc.) | Long | Equity-common | US | $259K | 104K | 0.10 |
| ALNYLAM PHARMACEUTICALS INC COMMON STOCK USD.01 (Alnylam Pharmaceuticals Inc.) | Long | Equity-common | US | $4M | 25K | 1.41 |
| ALTO NEUROSCIENCE INC COMMON STOCK USD.0001 (Alto Neuroscience Inc.) | Long | Equity-common | US | $107K | 9K | 0.04 |
| ALX ONCOLOGY HOLDINGS INC COMMON STOCK USD.001 (ALX Oncology Holdings Inc.) | Long | Equity-common | US | $2K | 220 | 0.00 |
| AMGEN INC COMMON STOCK USD.0001 (Amgen Inc.) | Long | Equity-common | US | $6M | 19K | 2.16 |
| ANAPTYSBIO INC COMMON STOCK USD.001 (AnaptysBio Inc.) | Long | Equity-common | US | $108K | 5K | 0.04 |
| ANNEXON INC COMMON STOCK (Annexon Inc.) | Long | Equity-common | US | $88K | 18K | 0.03 |
| APELLIS PHARMACEUTICALS INC COMMON STOCK USD.0001 (Apellis Pharmaceuticals Inc.) | Long | Equity-common | US | $627K | 16K | 0.23 |
| APOGEE THERAPEUTICS INC COMMON STOCK USD.00001 (Apogee Therapeutics Inc.) | Long | Equity-common | US | $703K | 15K | 0.26 |
| ARCELLX INC COMMON STOCK USD.001 (Arcellx Inc.) | Long | Equity-common | US | $566K | 11K | 0.21 |
| ARDELYX INC COMMON STOCK USD.000001 (Ardelyx Inc.) | Long | Equity-common | US | $422K | 62K | 0.16 |
| ARGENX SE ADR | Long | Equity-common | NL | $5M | 14K | 1.89 |
| ARVINAS INC COMMON STOCK USD.001 (Arvinas Inc.) | Long | Equity-common | US | $606K | 18K | 0.23 |
| ASCENDIS PHARMA A/S ADR DKK1.0 | Long | Equity-common | DK | $2M | 13K | 0.67 |
| ASTRAZENECA PLC ADR | Long | Equity-common | GB | $7M | 87K | 2.54 |
| ATARA BIOTHERAPEUTICS INC COMMON STOCK USD.0001 (Atara Biotherapeutics Inc.) | Long | Equity-common | US | $44K | 78K | 0.02 |
| AURA BIOSCIENCES INC COMMON STOCK USD.00001 (Aura Biosciences Inc.) | Long | Equity-common | US | $86K | 12K | 0.03 |
| AUTOLUS THERAPEUTICS PLC ADR GBP.0000001 | Long | Equity-common | GB | $162K | 39K | 0.06 |
| AVIDITY BIOSCIENCES INC COMMON STOCK (Avidity Biosciences Inc.) | Long | Equity-common | US | $1M | 54K | 0.54 |
| BEAM THERAPEUTICS INC COMMON STOCK USD.01 (Beam Therapeutics Inc.) | Long | Equity-common | US | $501K | 21K | 0.19 |
| BECTON DICKINSON and CO COMMON STOCK USD1.0 (Becton Dickinson and Company) | Long | Equity-common | US | $3M | 13K | 1.09 |
| BEIGENE LTD ADR USD.0001 (BeiGene Ltd.) | Long | Equity-common | US | $2M | 13K | 0.71 |
| BICYCLE THERAPEUTICS PLC ADR USD.01 | Long | Equity-common | GB | $537K | 24K | 0.20 |
| BIO-TECHNE CORP COMMON STOCK USD.01 (Bio-Techne Corporation) | Long | Equity-common | US | $2M | 22K | 0.63 |
| BIOCRYST PHARMACEUTICALS INC COMMON STOCK USD.01 (BioCryst Pharmaceuticals Inc.) | Long | Equity-common | US | $79K | 12K | 0.03 |
| BIOGEN INC COMMON STOCK USD.0005 (Biogen Inc.) | Long | Equity-common | US | $1M | 5K | 0.45 |
| BIOHAVEN LTD COMMON STOCK (Biohaven Ltd.) | Long | Equity-common | US | $1M | 35K | 0.46 |
| BIOMARIN PHARMACEUTICAL INC COMMON STOCK USD.001 (BioMarin Pharmaceutical Inc.) | Long | Equity-common | US | $1M | 14K | 0.40 |
| BLUEPRINT MEDICINES CORP COMMON STOCK USD.001 (Blueprint Medicines Corporation) | Long | Equity-common | US | $4M | 38K | 1.50 |
| BOSTON SCIENTIFIC CORP COMMON STOCK USD.01 (Boston Scientific Corporation) | Long | Equity-common | US | $4M | 56K | 1.57 |
| BRIGHTSPRING HEALTH SERVICES I COMMON STOCK USD100.0 (BrightSpring Health Services Inc.) | Long | Equity-common | US | $255K | 23K | 0.09 |
| BRUKER CORP COMMON STOCK USD.01 (Bruker Corporation) | Long | Equity-common | US | $545K | 8K | 0.20 |
| CABALETTA BIO INC COMMON STOCK USD.00001 (Cabaletta Bio Inc.) | Long | Equity-common | US | $106K | 10K | 0.04 |
| CARDINAL HEALTH INC COMMON STOCK (Cardinal Health Inc.) | Long | Equity-common | US | $871K | 9K | 0.32 |
| CARGO THERAPEUTICS INC COMMON STOCK USD.001 (Cargo Therapeutics Inc.) | Long | Equity-common | US | $650K | 34K | 0.24 |
| CELLDEX THERAPEUTICS INC COMMON STOCK USD.001 (Celldex Therapeutics Inc.) | Long | Equity-common | US | $834K | 25K | 0.31 |
| CENCORA INC COMMON STOCK USD.01 (Cencora Inc.) | Long | Equity-common | US | $568K | 3K | 0.21 |
| CENTENE CORP COMMON STOCK USD.001 (Centene Corporation) | Long | Equity-common | US | $1M | 19K | 0.51 |
| CENTESSA PHARMACEUTICALS PLC ADR USD.0001 | Long | Equity-common | US | $329K | 38K | 0.12 |
| CG ONCOLOGY INC COMMON STOCK (CG Oncology Inc.) | Long | Equity-common | US | $502K | 15K | 0.19 |
| CHUGAI PHARMACEUTICAL CO LTD COMMON STOCK (Chugai Pharmaceutical Co. Ltd.) | Long | Equity-common | JP | $338K | 11K | 0.13 |
| CIGNA GROUP/THE COMMON STOCK USD.01 (The Cigna Group) | Long | Equity-common | US | $5M | 14K | 1.86 |
| CORBUS PHARMACEUTICALS HOLDING COMMON STOCK USD.0001 (Corbus Pharmaceuticals Holdings Inc.) | Long | Equity-common | US | $175K | 4K | 0.07 |
| CRINETICS PHARMACEUTICALS INC COMMON STOCK USD.001 (Crinetics Pharmaceuticals Inc.) | Long | Equity-common | US | $884K | 20K | 0.33 |
| CYTOKINETICS INC COMMON STOCK USD.001 (Cytokinetics Incorporated) | Long | Equity-common | US | $483K | 10K | 0.18 |
| DAIICHI SANKYO CO LTD COMMON STOCK (Daiichi Sankyo Company Limited) | Long | Equity-common | JP | $717K | 20K | 0.27 |
| DANAHER CORP COMMON STOCK USD.01 (Danaher Corporation) | Long | Equity-common | US | $9M | 37K | 3.53 |
| DAY ONE BIOPHARMACEUTICALS INC COMMON STOCK USD.0001 (Day One Biopharmaceuticals Inc.) | Long | Equity-common | US | $33K | 2K | 0.01 |
| DENALI THERAPEUTICS INC COMMON STOCK USD.01 (Denali Therapeutics Inc.) | Long | Equity-common | US | $398K | 21K | 0.15 |
| DEXCOM INC COMMON STOCK USD.001 (DexCom Inc.) | Long | Equity-common | US | $2M | 14K | 0.60 |
| DISC MEDICINE INC COMMON STOCK USD.0001 (Disc Medicine Inc.) | Long | Equity-common | US | $137K | 4K | 0.05 |
| DYNE THERAPEUTICS INC COMMON STOCK USD.0001 (Dyne Therapeutics Inc.) | Long | Equity-common | US | $342K | 11K | 0.13 |
| EDWARDS LIFESCIENCES CORP COMMON STOCK USD1.0 (Edwards Lifesciences Corporation) | Long | Equity-common | US | $4M | 42K | 1.35 |
| ELANCO ANIMAL HEALTH INC COMMON STOCK (Elanco Animal Health Incorporated) | Long | Equity-common | US | $431K | 24K | 0.16 |
| ELEVANCE HEALTH INC COMMON STOCK USD.01 (Elevance Health Inc.) | Long | Equity-common | US | $10M | 19K | 3.86 |
| ELI LILLY + CO COMMON STOCK (Eli Lilly and Company) | Long | Equity-common | US | $30M | 36K | 11.11 |
| ENANTA PHARMACEUTICALS INC COMMON STOCK USD.01 (Enanta Pharmaceuticals Inc.) | Long | Equity-common | US | $50K | 4K | 0.02 |
| ENOVIS CORP COMMON STOCK USD.001 (Enovis Corporation) | Long | Equity-common | US | $201K | 4K | 0.07 |
| ENTRADA THERAPEUTICS INC COMMON STOCK USD.0001 (Entrada Therapeutics Inc.) | Long | Equity-common | US | $174K | 11K | 0.07 |
| EXACT SCIENCES CORP COMMON STOCK USD.01 (Exact Sciences Corporation) | Long | Equity-common | US | $686K | 15K | 0.26 |
| EYEPOINT PHARMACEUTICALS INC COMMON STOCK USD.01 (EyePoint Pharmaceuticals Inc.) | Long | Equity-common | US | $160K | 15K | 0.06 |
| GENEDX HOLDINGS CORP COMMON STOCK USD.0001 (GeneDX Holdings Corp.) | Long | Equity-common | US | $19K | 990 | 0.01 |
| GENEDX HOLDINGS CORP GENEDX HOLDINGS CORP (GeneDX Holdings Corp.) | Long | Equity-common | US | $170.89 | 7K | 0.00 |
| GENERATION BIO CO COMMON STOCK USD.0001 (Generation Bio Co.) | Long | Equity-common | US | $145K | 46K | 0.05 |
| GERON CORP COMMON STOCK USD.001 (Geron Corporation) | Long | Equity-common | US | $325K | 91K | 0.12 |
| GINKGO BIOWORKS HOLDINGS INC COMMON STOCK USD.0001 (Ginkgo Bioworks Holdings Inc.) | Long | Equity-common | US | $48K | 91K | 0.02 |
| GOSSAMER BIO INC COMMON STOCK USD.0001 (Gossamer Bio Inc.) | Long | Equity-common | US | $31K | 53K | 0.01 |
| GUARDANT HEALTH INC COMMON STOCK USD.00001 (Guardant Health Inc.) | Long | Equity-common | US | $348K | 13K | 0.13 |
| HAEMONETICS CORP COMMON STOCK USD.01 (Haemonetics Corporation) | Long | Equity-common | US | $215K | 3K | 0.08 |
| HCA HEALTHCARE INC COMMON STOCK USD.01 (HCA Healthcare Inc.) | Long | Equity-common | US | $3M | 9K | 1.16 |
| HELIX ACQUISITION CORP II COMMON STOCK USD.0001 (Helix Acquisition Corp. II) | Long | Equity-common | KY | $166K | 16K | 0.06 |
| HOLOGIC INC COMMON STOCK USD.01 (Hologic Inc.) | Long | Equity-common | US | $1M | 19K | 0.53 |
| HUMANA INC COMMON STOCK USD.1666666 (Humana Inc.) | Long | Equity-common | US | $2M | 4K | 0.59 |
| ICON PLC COMMON STOCK EUR.06 (Icon Public Limited Company) | Long | Equity-common | IE | $2M | 5K | 0.65 |
| IDEAYA BIOSCIENCES INC COMMON STOCK (IDEAYA Biosciences Inc.) | Long | Equity-common | US | $692K | 19K | 0.26 |
| IDEXX LABORATORIES INC COMMON STOCK USD.1 (IDEXX Laboratories Inc.) | Long | Equity-common | US | $497K | 1K | 0.19 |
| IGM BIOSCIENCES INC COMMON STOCK USD.01 (IGM Biosciences Inc.) | Long | Equity-common | US | $148K | 18K | 0.06 |
| IMMATICS NV COMMON STOCK (Immatics N.V.) | Long | Equity-common | DE | $401K | 36K | 0.15 |
| IMMUNEERING CORP COMMON STOCK USD.001 (Immuneering Corporation) | Long | Equity-common | US | $47K | 34K | 0.02 |
| IMMUNOCORE HOLDINGS PLC ADR GBP.0001 | Long | Equity-common | GB | $1M | 24K | 0.44 |
| IMMUNOCORE HOLDINGS PLC SR UNSECURED 144A 02/30 2.5 | Long | Debt | GB | $251K | – | 0.09 |
| IMMUNOME INC COMMON STOCK (Immunome Inc.) | Long | Equity-common | US | $496K | 33K | 0.18 |
| INSMED INC COMMON STOCK USD.01 (Insmed Incorporated) | Long | Equity-common | US | $3M | 52K | 1.06 |
| INSPIRE MEDICAL SYSTEMS INC COMMON STOCK USD.001 (Inspire Medical Systems Inc.) | Long | Equity-common | US | $629K | 4K | 0.23 |
| INSULET CORP COMMON STOCK USD.001 (Insulet Corporation) | Long | Equity-common | US | $586K | 3K | 0.22 |
| INTRA-CELLULAR THERAPIES INC COMMON STOCK USD.0001 (Intra-Cellular Therapies Inc.) | Long | Equity-common | US | $249K | 4K | 0.09 |
| INTUITIVE SURGICAL INC COMMON STOCK USD.001 (Intuitive Surgical Inc.) | Long | Equity-common | US | $12M | 29K | 4.38 |
| IONIS PHARMACEUTICALS INC COMMON STOCK USD.001 (Ionis Pharmaceuticals Inc.) | Long | Equity-common | US | $501K | 13K | 0.19 |
| IOVANCE BIOTHERAPEUTICS INC COMMON STOCK USD.000041666 (Iovance Biotherapeutics Inc.) | Long | Equity-common | US | $451K | 51K | 0.17 |
| JANUX THERAPEUTICS INC COMMON STOCK USD.001 (Janux Therapeutics Inc.) | Long | Equity-common | US | $161K | 3K | 0.06 |
| KRYSTAL BIOTECH INC COMMON STOCK USD.00001 (Krystal Biotech Inc.) | Long | Equity-common | US | $1M | 7K | 0.41 |
| KYMERA THERAPEUTICS INC COMMON STOCK USD.0001 (Kymera Therapeutics Inc.) | Long | Equity-common | US | $792K | 25K | 0.30 |
| KYVERNA THERAPEUTICS INC COMMON STOCK USD.00001 (Kyverna Therapeutics Inc.) | Long | Equity-common | US | $105K | 8K | 0.04 |
| LANTHEUS HOLDINGS INC COMMON STOCK USD.01 (Lantheus Holdings Inc.) | Long | Equity-common | US | $494K | 6K | 0.18 |
| LEGEND BIOTECH CORP ADR USD.0001 (Legend Biotech Corporation) | Long | Equity-common | US | $806K | 20K | 0.30 |
| LONGBOARD PHARMACEUTICALS INC COMMON STOCK USD.0001 (Longboard Pharmaceuticals Inc.) | Long | Equity-common | US | $404K | 21K | 0.15 |
| LYELL IMMUNOPHARMA INC COMMON STOCK USD.0001 (Lyell Immunopharma Inc.) | Long | Equity-common | US | $385K | 139K | 0.14 |
| MACROGENICS INC COMMON STOCK USD.01 (MacroGenics Inc.) | Long | Equity-common | US | $103K | 25K | 0.04 |
| MADRIGAL PHARMACEUTICALS INC COMMON STOCK USD.0001 (Madrigal Pharmaceuticals Inc.) | Long | Equity-common | US | $2M | 7K | 0.65 |
| MASIMO CORP COMMON STOCK USD.001 (Masimo Corporation) | Long | Equity-common | US | $106K | 854 | 0.04 |
| MCKESSON CORP COMMON STOCK USD.01 (McKesson Corporation) | Long | Equity-common | US | $1M | 2K | 0.47 |
| MERCK and CO INC COMMON STOCK USD.5 (Merck and Co. Inc.) | Long | Equity-common | US | $11M | 87K | 4.05 |
| MERUS NV COMMON STOCK EUR.05 (Merus N.V.) | Long | Equity-common | NL | $938K | 18K | 0.35 |
| MIRUM PHARMACEUTICALS INC COMMON STOCK (Mirum Pharmaceuticals Inc.) | Long | Equity-common | US | $199K | 8K | 0.07 |
| MODERNA INC COMMON STOCK USD.0001 (Moderna Inc.) | Long | Equity-common | US | $1M | 9K | 0.45 |
| MOLINA HEALTHCARE INC COMMON STOCK USD.001 (Molina Healthcare Inc.) | Long | Equity-common | US | $3M | 10K | 1.13 |
| MONTE ROSA THERAPEUTICS INC COMMON STOCK USD.0001 (Monte Rosa Therapeutics Inc.) | Long | Equity-common | US | $156K | 38K | 0.06 |
| MOONLAKE IMMUNOTHERAPEUTICS COMMON STOCK USD.0001 | Long | Equity-common | CH | $953K | 23K | 0.36 |
| MORPHIC HOLDING INC COMMON STOCK USD.0001 (Morphic Holding Inc.) | Long | Equity-common | US | $456K | 15K | 0.17 |
| NEUMORA THERAPEUTICS INC COMMON STOCK USD.0001 (Neumora Therapeutics Inc.) | Long | Equity-common | US | $166K | 17K | 0.06 |
| NEUROCRINE BIOSCIENCES INC COMMON STOCK USD.001 (Neurocrine Biosciences Inc.) | Long | Equity-common | US | $2M | 15K | 0.74 |
| NOVO NORDISK A/S ADR | Long | Equity-common | DK | $4M | 33K | 1.65 |
| NOVOCURE LTD COMMON STOCK (NovoCure Limited) | Long | Equity-common | JE | $806K | 37K | 0.30 |
| NUVATION BIO INC COMMON STOCK USD.0001 (Nuvation Bio Inc.) | Long | Equity-common | US | $50K | 16K | 0.02 |
| OCULAR THERAPEUTIX INC COMMON STOCK USD.0001 (Ocular Therapeutix Inc.) | Long | Equity-common | US | $87K | 15K | 0.03 |
| ORCHESTRA BIOMED HOLDINGS INC COMMON STOCK USD.0001 (Orchestra Biomed Holdings Inc.) | Long | Equity-common | US | $133K | 19K | 0.05 |
| ORIC PHARMACEUTICALS INC COMMON STOCK USD.0001 (ORIC Pharmaceuticals Inc.) | Long | Equity-common | US | $201K | 22K | 0.08 |
| OSCAR HEALTH INC COMMON STOCK USD.00001 (Oscar Health Inc.) | Long | Equity-common | US | $970K | 49K | 0.36 |
| PACIFIC BIOSCI OF CALIFORNIA COMMON STOCK USD.0001 (Pacific Biosciences of California Inc.) | Long | Equity-common | US | $66K | 37K | 0.02 |
| PENUMBRA INC COMMON STOCK USD.001 (Penumbra Inc.) | Long | Equity-common | US | $3M | 14K | 1.01 |
| PHARMING GROUP NV COMMON STOCK EUR.01 (Pharming Group N.V.) | Long | Equity-common | NL | $116K | 130K | 0.04 |
| PHARVARIS NV COMMON STOCK EUR.12 (Pharvaris B.V.) | Long | Equity-common | NL | $278K | 15K | 0.10 |
| PLIANT THERAPEUTICS INC COMMON STOCK (Pliant Therapeutics Inc.) | Long | Equity-common | US | $163K | 13K | 0.06 |
| PRAXIS PRECISION MEDICINES INC COMMON STOCK USD.0001 (Praxis Precision Medicines Inc.) | Long | Equity-common | US | $336K | 7K | 0.13 |
| PRELUDE THERAPEUTICS INC COMMON STOCK USD.0001 (Prelude Therapeutics Incorporated) | Long | Equity-common | US | $66K | 17K | 0.02 |
| PROCEPT BIOROBOTICS CORP COMMON STOCK USD.00001 (PROCEPT BioRobotics Corporation) | Long | Equity-common | US | $727K | 11K | 0.27 |
| PROTAGONIST THERAPEUTICS INC COMMON STOCK USD.00001 (Protagonist Therapeutics Inc.) | Long | Equity-common | US | $383K | 14K | 0.14 |
| PROTHENA CORP PLC COMMON STOCK USD.01 (Prothena Corporation Public Limited Company) | Long | Equity-common | IE | $298K | 14K | 0.11 |
| RAPT THERAPEUTICS INC COMMON STOCK (RAPT Therapeutics Inc.) | Long | Equity-common | US | $16K | 4K | 0.01 |
| REGENERON PHARMACEUTICALS INC COMMON STOCK USD.001 (Regeneron Pharmaceuticals Inc.) | Long | Equity-common | US | $8M | 8K | 2.99 |
| RELAY THERAPEUTICS INC COMMON STOCK USD.001 (Relay Therapeutics Inc.) | Long | Equity-common | US | $304K | 47K | 0.11 |
| REPLIGEN CORP COMMON STOCK USD.01 (Repligen Corporation) | Long | Equity-common | US | $739K | 5K | 0.28 |
| REPLIMUNE GROUP INC COMMON STOCK USD.001 (Replimune Group Inc.) | Long | Equity-common | US | $151K | 29K | 0.06 |
| REVOLUTION MEDICINES INC COMMON STOCK (Revolution Medicines Inc.) | Long | Equity-common | US | $1M | 29K | 0.41 |
| REVOLUTION MEDICINES INC WARRANTS CALL EXP 14NOV28 (Revolution Medicines Inc.) | Long | Equity-common | US | $1K | 7K | 0.00 |
| REVVITY INC COMMON STOCK USD1.0 (Revvity Inc.) | Long | Equity-common | US | $645K | 6K | 0.24 |
| RHYTHM PHARMACEUTICALS INC COMMON STOCK (Rhythm Pharmaceuticals Inc.) | Long | Equity-common | US | $168K | 5K | 0.06 |
| ROCKET PHARMACEUTICALS INC COMMON STOCK USD.01 (Rocket Pharmaceuticals Inc.) | Long | Equity-common | US | $488K | 23K | 0.18 |
| ROWE T PRICE GOV RES FD 20340919 00000.0000000000 | Long | Short-term investment vehicle | US | $130K | 130K | 0.05 |
| SAGE THERAPEUTICS INC COMMON STOCK USD.0001 (Sage Therapeutics Inc.) | Long | Equity-common | US | $183K | 17K | 0.07 |
| SANA BIOTECHNOLOGY INC COMMON STOCK USD.0001 (Sana Biotechnology Inc.) | Long | Equity-common | US | $428K | 57K | 0.16 |
| SAREPTA THERAPEUTICS INC COMMON STOCK USD.0001 (Sarepta Therapeutics Inc.) | Long | Equity-common | US | $526K | 4K | 0.20 |
| SARTORIUS AG PREFERENCE | Long | Equity-preferred | DE | $569K | 2K | 0.21 |
| SCC GOVERMENT MM GVXX 20301231 00001.0000000000 (State Street Bank and Trust Company) | Long | Short-term investment vehicle | US | $1M | 1M | 0.50 |
| SCHOLAR ROCK HOLDING CORP COMMON STOCK USD.001 (Scholar Rock Holding Corporation) | Long | Equity-common | US | $347K | 37K | 0.13 |
| SENSORION SA COMMON STOCK EUR.1 | Long | Equity-common | FR | $152K | 182K | 0.06 |
| SIEMENS HEALTHINEERS AG COMMON STOCK | Long | Equity-common | DE | $410K | 7K | 0.15 |
| SOLENO THERAPEUTICS INC COMMON STOCK USD.001 (Soleno Therapeutics Inc.) | Long | Equity-common | US | $329K | 8K | 0.12 |
| SOMALOGIC INC WARRANTS CALL EXP 31AUG26 (SomaLogic Inc.) | Long | Equity-common | US | $292.9 | 3K | 0.00 |
| SONOVA HOLDING AG COMMON STOCK CHF.05 | Long | Equity-common | CH | $591K | 2K | 0.22 |
| SPRINGWORKS THERAPEUTICS INC COMMON STOCK USD.0001 (SpringWorks Therapeutics Inc.) | Long | Equity-common | US | $923K | 22K | 0.34 |
| SPYRE THERAPEUTICS INC COMMON STOCK USD.0001 (Spyre Therapeutics Inc.) | Long | Equity-common | US | $220K | 6K | 0.08 |
| STRUCTURE THERAPEUTICS INC ADR USD.0001 (Structure Therapeutics Inc.) | Long | Equity-common | US | $513K | 15K | 0.19 |
| STRYKER CORP COMMON STOCK USD.1 (Stryker Corporation) | Long | Equity-common | US | $10M | 29K | 3.63 |
| SURGERY PARTNERS INC COMMON STOCK USD.01 (Surgery Partners Inc.) | Long | Equity-common | US | $470K | 17K | 0.18 |
| TARSUS PHARMACEUTICALS INC COMMON STOCK USD.0001 (Tarsus Pharmaceuticals Inc.) | Long | Equity-common | US | $164K | 5K | 0.06 |
| TAYSHA GENE THERAPIES INC COMMON STOCK USD.00001 (Taysha Gene Therapies Inc.) | Long | Equity-common | US | $61K | 18K | 0.02 |
| TENET HEALTHCARE CORP COMMON STOCK USD.05 (Tenet Healthcare Corporation) | Long | Equity-common | US | $2M | 16K | 0.80 |
| THERMO FISHER SCIENTIFIC INC COMMON STOCK USD1.0 (Thermo Fisher Scientific Inc.) | Long | Equity-common | US | $12M | 22K | 4.65 |
| ULTRAGENYX PHARMACEUTICAL INC COMMON STOCK USD.001 (Ultragenyx Pharmaceutical Inc.) | Long | Equity-common | US | $792K | 20K | 0.30 |
| UNITEDHEALTH GROUP INC COMMON STOCK USD.01 (UnitedHealth Group Incorporated) | Long | Equity-common | US | $17M | 35K | 6.50 |
| VAXCYTE INC COMMON STOCK USD.001 (Vaxcyte Inc.) | Long | Equity-common | US | $1M | 15K | 0.39 |
| VEEVA SYSTEMS INC COMMON STOCK USD.00001 (Veeva Systems Inc.) | Long | Equity-common | US | $279K | 2K | 0.10 |
| VERA THERAPEUTICS INC COMMON STOCK USD.001 (Vera Therapeutics Inc.) | Long | Equity-common | US | $686K | 18K | 0.26 |
| VERTEX PHARMACEUTICALS INC COMMON STOCK USD.01 (Vertex Pharmaceuticals Incorporated) | Long | Equity-common | US | $7M | 15K | 2.53 |
| VIATRIS INC COMMON STOCK | Long | Equity-common | US | $307K | 29K | 0.11 |
| VIKING THERAPEUTICS INC COMMON STOCK USD.00001 (Viking Therapeutics Inc.) | Long | Equity-common | US | $159K | 3K | 0.06 |
| VOYAGER THERAPEUTICS INC COMMON STOCK USD.001 (Voyager Therapeutics Inc.) | Long | Equity-common | US | $181K | 22K | 0.07 |
| WAVE LIFE SCIENCES LTD COMMON STOCK (Wave Life Sciences Ltd.) | Long | Equity-common | US | $263K | 43K | 0.10 |
| WEST PHARMACEUTICAL SERVICES I COMMON STOCK USD.25 (West Pharmaceutical Services Inc.) | Long | Equity-common | US | $909K | 3K | 0.34 |
| XENCOR INC COMMON STOCK USD.01 (Xencor Inc.) | Long | Equity-common | US | $452K | 19K | 0.17 |
| ZAI LAB LTD ADR USD.00006 (Zai Lab Limited) | Long | Equity-common | CN | $518K | 29K | 0.19 |
| ZENTALIS PHARMACEUTICALS INC COMMON STOCK USD.001 (Zentalis Pharmaceuticals Inc.) | Long | Equity-common | US | $321K | 27K | 0.12 |
| ZIMMER BIOMET HOLDINGS INC COMMON STOCK USD.01 (Zimmer Biomet Holdings Inc.) | Long | Equity-common | US | $685K | 6K | 0.26 |
Address
John Hancock Funds II
200 Berkeley Street
Boston
Massachusetts
02116
United States of America
Websites
Directors
Hassell H. McClellan
James R. Boyle
Peter S. Burgess
William H. Cunningham
Grace K. Fey
Deborah C. Jackson
Gregory A. Russo
Steven R. Pruchansky
Andrew G. Arnott
Frances G. Rathke
Noni L. Ellison
Dean C. Garfield
Patricia Lizarraga
Paul Lorentz
Transfer Agents
John Hancock Signature Services, Inc.
Pricing Services
Refinitiv
ICE Data Services
Pricing Direct
S&P Global Market Intelligence
Bloomberg LP
State Street Bank and Trust Company
Custodians
State Street Bank and Trust Company
Shareholder Servicing Agents
John Hancock Signature Services, Inc.
Admins
John Hancock Investment Management LLC
Brokers
Merrill Lynch, Pierce, Fenner & Smith Incorporated
Pershing LLC